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What causes muscle spasm?

A wide range of factors can trigger a muscle spasm. Some are obvious, like heavy exercise or injuries that cause a muscle to be strained, stretched, pulled tightly, or ruptured.

Eight out of ten people say certain day-to-day activities contribute to muscle spasm.3

Who gets muscle spasm?


AMRIX People

Four out of five adults have experienced muscle spasm.3

Anyone can get a muscle spasm. Muscle spasm can occur regardless of the activity: while sleeping, exercising, or even sitting at a desk.

Most people have had a muscle spasm at least once. In a recent nationwide survey of adults, 83% said they have experienced a muscle spasm, and half of them reported they had experienced another episode of muscle spasm within three months of the original spasm.3

Muscle spasm and pain are common in people with low back or neck strains. These are called musculoskeletal conditions because they affect muscle, bone and the connective tissue.

  • Low-back pain affects as many as 70% to 85% of adults at some point in their lives4
  • Neck pain affects up to 67% of adults at some point in their lives5

If you experience muscle spasm, ask your doctor if AMRIX may be right for you.

AMRIX® (Cyclobenzaprine Hydrochloride Extended-Release Capsules) is a prescription medicine to be used along with rest and physical therapy to help control muscle spasm associated with acute, painful musculoskeletal conditions. AMRIX should only be taken for short periods (up to two or three weeks). It should be taken at about the same time each day.

Certain medicines may cause serious or potentially life-threatening consequences when taken in combination with AMRIX, so tell your doctor if you are taking any medicines.

You should not use AMRIX if you:

  • Are sensitive to any of its ingredients
  • Are taking certain antidepressants, such as monoamine oxidase inhibitors (MAOIs)
  • Are 65 years old or older
  • Have liver problems
  • Have certain types of heart problems
  • Have an overactive thyroid

Before taking AMRIX, talk to your doctor about all of your medical conditions, including any history of heart problems, urinary problems, or glaucoma.

AMRIX may affect your ability to perform certain hazardous tasks, such as operating machinery or driving a motor vehicle, especially when used with alcohol or other sedatives.

Side effects of AMRIX may include dry mouth, dizziness, fatigue, nausea, upset stomach, constipation, and drowsiness. Click here for full Prescribing Information.

AMRIX is distributed by Cephalon and produced with Eurand Diffucaps® technology. For more information about AMRIX, please call Cephalon at 1-800-896-5855.